In venues such as Carnegie Hall, Lincoln Center, Walt Disney Concert Hall, Kennedy Center, and Park Avenue Armory, Bloom has guest conducted the Los Angeles Philharmonic, American Composers Orchestra, Washington National Opera, Opera Omaha, Central City Opera, Tri-Cities Opera, Bang on a Can All-Stars, The Crossing, Ensemble Connect, and Kronos Quartet and worked with such soloists and Dashon Burton, David Byrne, Anthony Roth Costanzo, Helga Davis, Isabel Leonard, Iarla Ó Lionáird, Courtney Love, Hila Plitmann, Dawn Upshaw, and Andrew Yee, and composers Clarice Assad, Courtney Bryan, John Corigliano, Donnacha Dennehy, Du Yun, inti figgis-vizueta, Michael Gordon, Nathalie Joachim, David Lang, Tania León, Andrew Norman, and Julia Wolfe. He conducted the opening of Lincoln Center’s 2024 Summer for the City with opera standards and originals featuring drag artists Sapphira Cristál, Monét X Change, and Thorgy Thor. 

Since 2022, he has been Artistic Director of Queer Urban Orchestra, the only orchestra in the Northeast rooted in the LGBTQ+ community. He is also Co-Artistic Director of Contemporaneous and Principal Conductor of both Present Music and the New York University Orchestra, where he also teaches conducting. He has conducted over 500 world premieres, including the orchestral version of Philip Glass’ La Belle et la Bête with Jean Cocteau’s 1946 film, Dylan Mattingly’s six-hour opera Stranger Love, and Raven Chacon’s Voiceless Mass, which went on to win the 2022 Pulitzer Prize. He has recorded for the Nonesuch, Sony Masterworks, Cantaloupe, New Amsterdam, Innova, New Focus, Starkland, Kairos, and Navona labels.